Let G be a finite group and p(G) be the set of all prime divisors of |G|. The prime graph of G is a simple graph G (G) with vertex set p(G) and two distinct vertices p and q in p(G) are adjacent by an edge if an only if G has an element of order pq. In this case, we write p ~ q. Let |G|=p a11. p a22…p akk, where p1<p2<…<pk are primes. For p Îp(G), let deg (p)=|{qÎp(G) |p ~ q}| be the degree of p in the graph G(G), we define D(G)=(deg (p1), deg (p2),…, deg (pk)) and call it the degree pattern of G. A group G is called k -fold OD-characterizable if there exist exactly k non-isomorphic groups S such that |G|=|S| and D(G)=D(S). Moreover, a 1-fold OD-characterizable group is simply called an OD-characterizable group. Let L=S4 (4) be the projective symplectic group in dimension 4 over a field with 4 elements. In this article, we classify groups with the same order and degree pattern as an almost simple group related to L. Since Aut (L)@Z4 hence almost simple groups related toL are L, L: 2 or L: 4. In fact, we prove that L, L: 2 and L: 4 are OD-characterizable.